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EPIDERMAL GROWTH FACTOR
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DeCS
Descriptor
English
:
Epidermal Growth Factor
Descriptor
Spanish
:
Factor de Crecimiento Epidérmico
Descriptor
Portuguese
:
Fator de Crescimento Epidérmico
Synonyms
English
:
Epidermal Growth Factor-Urogastrone
Urogastrone
EGF
Tree Number:
D06.472.317.350
D12.644.276.561
D12.776.467.561
D23.529.561
Definition
English
:
A 6-kDa polypeptide
growth
factor initially discovered in mouse submaxillary glands. Human
epidermal growth factor
was originally isolated from
urine
based on its ability to inhibit gastric secretion and called urogastrone.
EPIDERMAL GROWTH FACTOR
exerts a wide variety of biological effects including the promotion of proliferation and differentiation of mesenchymal and
epithelial cells.
See Related
English
:
Anti-Ulcer Agents
Gastrointestinal Agents
Receptor, Epidermal Growth Factor
History Note
English
:
2000(1982); use PEPTIDES 1977-1981; for UROGASTRONE use GASTROINTESTINAL HORMONES 1963-1981
Allowable Qualifiers
English
:
analogs & derivatives
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
urine
Record Number:
4896
Unique Identifier:
D004815
Occurrence in VHL
:
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